Ookami to Koushinryou: MERCHANT MEETS THE WISE WOLF 2nd Season

Centers around the field of economics.

Prominently features a romance between a man and a woman, not inherently sexual.

Partially or completely set in the Middle Ages or a Middle Ages-inspired setting. Commonly features elements such as European castles and knights.

Prominently features romantic relations between people with a significant age difference.

Main character is female.